EIF4E Polyclonal Antibody
- Catalog Number : A340505
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Introduction
Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
General Information
| Reactivity | Rat, Mouse, Monkey |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P06730 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human eIF4E around the non-phosphorylation site of Ser209. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | AUTS19,CBP,eIF 4E,eIF 4F 25 kDa subunit,EIF 4F,eIF-4E,eIF-4F 25 kDa subunit,eIF4E,EIF4E1,EIF4EL1,EIF4F,Eukaryotic translation initiation factor 4 E,Eukaryotic translation initiation factor 4E,Eukaryotic translation initiation factor 4E like 1,IF4E,Messanger RNA Cap Binding Protein eIF 4E,MGC111573,mRNA cap binding protein,mRNA cap-binding protein |
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