Protein Biology

Recombinant Human ACE2 protein, His Tag

  • Catalog Number : P0051
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Introduction

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin, and angiotensin II to angiotensin. ACE-2 is also able to hydrolyze apelin and dynorphin with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. The recombinant Human ACE2 protein, His Tag consists of 734 amino acids and predicts a molecular mass of 85.1 kDa.

General Information

Tested Cell HEK293 Cells
Purity >95% as determined by SDS-PAGE
Molecular Weight 85.1 kDa
Formula Lyophilized from sterile PBS, pH 7.4.
Solubility Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Expression region Sequence Met1-Ser740
Protein Info Human ACE2
Tag Info 6XHis-Tag
Storage instruction Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid re
Alias Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2

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