COVID-19 , COVID-19 Related Compounds

GRL-0617

  • Catalog Number : C5120
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Introduction

GRL-0617 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 0.6 uM, Ki of 0.49 uM; inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 14.5 uM, has no associated cytotoxicity and no inhibition for host DUBs (human deubiquitinating enzymes HAUSP, USP18, UCH-L1, UCH-L3). SARS-CoV Infection Preclinical

General Information

Cas No. 1093070-16-6
Purity >98%
Molecular Weight 304.393
Formula C20H20N2O
Solubility DMSO : 125 mg/mL
Storage instruction 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Alias GRL0617;GRL 0617

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