Antibody, Primary Antibody, Monoclonal Antibody

anti-PD-L1 (Avelumab)

  • Catalog Number : A510006
  • Number : A510006-1mg
  • Size:
    Qty :
  • Price : Request Inquiry
  • Download DataSheet print

Introduction

Avelumab biosimilar is a programmed death ligand-1 (PD-L1) blocking antibody and prevents its interaction with the inhibitory T-cell receptor, PD-1 (programmed cell death protein 1). Upon binding, avelumab promotes T-cell reactivation and restores T-cell-mediated immune response against tumor cells. Avelumab is also the only PD-L1 antibody so far to also induce antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing PD-L1.

General Information

Reactivity Human
Application Functional Assay
Host CHO cells
Clonality Monoclonal
Conjugate Non-conjugated
Isotype Human IgG1
Cas No. 1537032-82-8
Purity >95%; < 0.75 EU/mg as determined by the LAL method
Molecular Weight 150 kDa
Storage buffer 0.01 M phosphate buffered saline (PBS) pH 7.2
Storage instruction This solution is stable for at least 4 weeks when stored at 2-8°C. For long term storage aseptically aliquot and store at –80°C.Avoid repeated freeze/thaw cycles.

Recently Viewed Products

gotop link
Customized Product Contact Us
0