Protein Biology, COVID-19 , COVID-19 (SARS-CoV-2) proteins

Recombinant SARS-COV-2 Nucleocapsid Protein (His Tag)

  • Catalog Number : P0077
  • Number : P0077-100ug
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Introduction

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry.
Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

General Information

Reactivity Virus
Host Baculovirus-Insect Cells
Purity > 90 % as determined by reducing SDS-PAGE
Molecular Weight 47.08 kDa
Formula LyopHilized from sterile 20mM Tris, 500mM NaCl, pH8.0, 10% glycerol.
Storage instruction Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Alias SARS-COV-2 coronavirus NP Protein;SARS-COV-2 np Protein;SARS-COV-2 novel coronavirus Nucleoprotein Protein

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