Antibody, Antibody Sampler Kit
Cell Cycle Regulation Antibody Sampler Kit II
- Catalog Number : AK0199
- Number :
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Size:
Qty : - Price : Request Inquiry
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Introduction
The critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of cdc2 at Tyr15 and Thr14. Phosphorylation of cdc2 by the protein kinases Wee1 and Myt1 at Thr14 and Tyr15 results in inhibition of cdc2. Progression through the G1/S checkpoint and initiation of DNA replication requires cyclin E; traversing the G2/M checkpoint to initiate mitosis requires cyclin B, and cyclin A may be required for both S-phase and M-phase. The versatile p21 cyclin-dependent kinase inhibitor, which interacts with several cyclin-CDK complexes to regulate cyclin-CDK during the cell cycle, is regulated by phosphorylation and ubiquitin-mediated degradation. Phosphorylation of histone H3 at Ser10 and neighboring residues correlates with chromosomal condensation, which is essential for segregation of chromosomes during mitosis.
General Information
| Reactivity | Human, Mouse, Rabbit |
|---|---|
| Application | WB, ELISA |
| Host | Rabbit |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Research topic | Cell Cycle Regulation |
PRODUCT INCLUDES
|
Cat No. |
Product name |
Quantity |
Applications |
Reactivity |
Host |
|
A340205 |
Phospho-CDK1 (Tyr15) Polyclonal Antibody |
20μL |
WB, ELISA |
Human, Mouse, Rat, Monkey |
Rabbit |
|
A340117 |
Cyclin B1 Polyclonal Antibody |
20μL |
WB, ELISA |
Human |
Rabbit |
|
A340235 |
Phospho-Histone H3 (Ser10) Polyclonal Antibody |
20μL |
WB, IHC, IF, ELISA |
Human, Mouse, Rat |
Rabbit |
|
A340600 |
PKMYT1 Polyclonal Antibody |
20μL |
WB, IHC, ELISA |
Human |
Rabbit |
|
A340745 |
p21 Polyclonal Antibody |
20μL |
WB, ELISA |
Human |
Rabbit |
|
A340307 |
Phospho-WEE1 (Ser642) Polyclonal Antibody |
20μL |
WB, ELISA |
Human, Mouse, Rat |
Rabbit |
|
A1013s |
Goat Anti-Rabbit IgG (H+L) (peroxidase/HRP conjugated) |
120μL |
WB, ELISA |
Rabbit |
Goat |
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