Protein Biology

Glycyrrhizic acid >98%

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Introduction

Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.

General Information

Cas No. 1405-86-3
Purity >98%
Molecular Weight 822.93
Formula C₄₂H₆₂O₁₆
Tag Info Virus Protease
Storage instruction Powder:-20°C/3 years ,4°C/2 years

Mice[3] NOD.H-2h4 mice are fed in the animal house until 4 weeks of age. A total of 24 male mice are then randomly separated into three different groups (n=8 per group). Mice in the control group are given sterile water without supplement. Mice in the iodine supplement (NaI) group are given 0.005% NaI in the drinking water. Mice in the NaI+Glycyrrhizic acid group are treated with 50 mg/kg Glycyrrhizic acid once daily for 4 weeks, administered via intraperitoneal injection after 8 weeks of iodine supplementation. Thyroid tissues are removed surgically under anesthesia, washed with cold saline, blotted on filter paper and weighed using an electronic balance. The thyroid gland tissues are then stored at -80°C until use[3] . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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