Antibody, In Vivo Mab

anti-IL-6R (Tocilizumab)

  • Catalog Number : A510031
  • Number : A510031-1mg
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Introduction

Tocilizumab is a recombinant humanized anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin IgG1κ (gamma 1, kappa) subclass with a typical H2L2 polypeptide structure. Each light chain and heavy chain consists of 214 and 448 amino acids, respectively. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds.

General Information

Reactivity Human
Application Functional Assay
Host CHO cells
Clonality Monoclonal
Conjugate Non-conjugated
Isotype Human IgG1
Cas No. 375823-41-9
Purity >95%; < 0.75 EU/mg as determined by the LAL method
Molecular Weight 148 kDa
Storage buffer 0.01 M phosphate buffered saline (PBS) pH 7.2
Storage instruction This solution is stable for at least 4 weeks when stored at 2-8°C. For long term storage aseptically aliquot and store at –80°C.Avoid repeated freeze/thaw cycles.
Alias MRA, Atlizumab

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