Recombinant Human Tumor necrosis factor alpha(TNFα) Protein
- Catalog Number : P0074
- Number : P0074
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Introduction
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
General Information
| Reactivity | Human |
|---|---|
| Host | HEK293 Cells |
| Purity | >90% (SDS-PAGE) |
| Molecular Weight | 45.8 kDa |
| Formula | Lyophilized from sterile PBS, pH 7.4 |
| Storage instruction | Samples are stable for twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
| Alias | DIF; TNF-alpha; TNFA; TNFSF2 |
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