EIF4G1 Polyclonal Antibody
- Catalog Number : A340161
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Introduction
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
General Information
| Application | WB, IHC, ELISA |
|---|---|
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q04637 |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human EIF4G1 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | DKFZp686A1451,eIF 4 gamma 1,eIF 4G 1,eIF 4G1,eIF-4-gamma 1,eIF-4G 1,eIF-4G1,EIF4 gamma,EIF4F,EIF4G,EIF4G1,EIF4GI,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,p220 |
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