Phospho-SYK (Tyr525) Polyclonal Antibody
- Catalog Number : A340339
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Introduction
SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing.
General Information
| Reactivity | Rat, Mouse, Monkey |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P43405 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human Syk around the phosphorylation site of Tyr525 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | EC 2.7.10.2,kinase Syk,KSYK,KSYK,p72-Syk,p72syk,Spleen tyrosine kinase,Syk,Tyrosine protein kinase SYK,Tyrosine-protein kinase SYK |
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