FYN Polyclonal Antibody
- Catalog Number : A340529
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Introduction
Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC. Phosphorylates RUNX3.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P06241 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human Fyn around the non-phosphorylation site of Tyr530. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | C syn protooncogene,Fyn,FYN oncogene related to SRC FGR YES,FYN,OKT3 induced calcium influx regulator,P59 FYN,p59-Fyn,Protein tyrosine kinase fyn,Proto oncogene tyrosine protein kinase fyn,Proto-oncogene c-Fyn,Proto-oncogene Syn,Protooncogene Syn,SLK,Src like kinase,Src yes related novel gene,Src-like kinase,Src/yes related novel,SYN,Tyrosine kinase p59fyn T,Tyrosine kinase p59fyn(T),Tyrosine-protein kinase Fyn |
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