PDGFR-β Polyclonal Antibody
- Catalog Number : A340628
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Introduction
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IF, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P09619 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human PDGFR-β around the non-phosphorylation site of Tyr751. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | Beta platelet derived growth factor receptor,Beta-type platelet-derived growth factor receptor,CD 140B,CD140 antigen-like family member B,CD140b,CD140b antigen,IBGC4,IMF1,JTK12,OTTHUMP00000160528,PDGF R beta,PDGF-R-beta,PDGFR 1,PDGFR,PDGFR beta,PDGFR1,PDGFRB,PGFRB,Platelet derived growth factor receptor 1,Platelet derived growth factor receptor beta,Platelet derived growth factor receptor beta polypeptide |
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