Chemical, Inhibitor

Fludarabine

  • Catalog Number : C4110
  • Number : C4110-10mg
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Introduction

Fludarabine is a prodrμg converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair. Induces apoptosis of cancer cells and RNA transcription inhibitor.DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription

General Information

Application Chemical, Inhibitor
Cas No. 21679-14-1
Purity ≥98%
Molecular Weight 285.23
Formula C10H12FN5O4
Solubility Soluble in water (<1 mg/mL at 25 °C), DMSO (57 mg/mL at 25 °C), and ethanol (<1 mg/mL at 25 °C).
Storage instruction Store at 2-8℃
Alias 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine

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