Introduction
Fludarabine is a prodrμg converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair. Induces apoptosis of cancer cells and RNA transcription inhibitor.DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription
General Information
| Application | Chemical, Inhibitor |
|---|---|
| Cas No. | 21679-14-1 |
| Purity | ≥98% |
| Molecular Weight | 285.23 |
| Formula | C10H12FN5O4 |
| Solubility | Soluble in water (<1 mg/mL at 25 °C), DMSO (57 mg/mL at 25 °C), and ethanol (<1 mg/mL at 25 °C). |
| Storage instruction | Store at 2-8℃ |
| Alias | 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine |
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