Phospho-BCL2 (Ser70) Polyclonal Antibody
- Catalog Number : A340198
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Introduction
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
General Information
Reactivity | Monkey |
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Application | WB, IHC, ELISA, IP |
Clonality | Polyclonal |
Conjugate | Non-conjugated |
Uniprot | P10415 |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Ser70 |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
Alias | Apoptosis regulator Bcl 2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl2,AW986256,B cell CLL/lymphoma 2,B cell leukemia/lymphoma 2,Bcl-2,Bcl2,BCL2,C430015F12Rik,D630044D05Rik,D830018M01Rik,Leukemia/lymphoma,B-cell,2,Oncogene B-cell leukemia 2,PPP1R50,Protein phosphatase 1,regulatory subunit 50 |