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Name Phospho-PLCG2 (Tyr753) Polyclonal Antibody
Catalog# A340335
Type Primary Antibody
Reactivity Rat, Human, Mouse
Application WB, IHC, ELISA
Host Rabbit
Clonality Polyclonal
Conjugate Non-conjugated
Description The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Uniprot P16885
Isotype IgG
Immunogen Synthesized peptide derived from human PLC γ2 around the phosphorylation site of Tyr753
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2,EC 3.1.4.11,Phosphoinositide phospholipase C,Phosphoinositide phospholipase C-gamma-2,Phospholipase C gamma 2,Phospholipase C,gamma 2 (phosphatidylinositol specific),Phospholipase C-gamma-2,Phospholipase C-IV,PLC 2,PLC gamma 2,PLC IV,PLC-gamma-2,PLC-IV,Plcg2,PLCG2
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A340335

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