XRCC5 Polyclonal Antibody
- Catalog Number : A340579
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Introduction
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
General Information
| Reactivity | Monkey |
|---|---|
| Application | WB, IF, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P13010 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Ku-80 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | 86 kDa subunit of Ku antigen,ATP dependent DNA helicase 2 subunit 2,ATP dependent DNA helicase II 80 kDa subunit,ATP dependent DNA helicase II 86 Kd subunit,ATP dependent DNA helicase II,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box binding factor 85 kDa,CTC box-binding factor 85 kDa subunit,CTC85,CTCBF,DNA repair protein XRCC5,KARP 1,KARP1,Ku 80,Ku autoantigen 80kDa,Ku80,Ku86,Ku86 autoantigen related protein 1,KUB 2,KUB2,Lupus Ku autoantigen protein p86,NFIV,Nuclear factor IV,Thyroid lupus autoantigen,Thyroid-lupus autoantigen,TLAA,X ray repair complementing defective repair in Chinese hamster cells 5 (double strand break rejoining),X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining),X-ray repair cross-complementing protein 5,Xray repair complementing defective repair in Chinese hamster cells 5,XRCC 5,XRCC5,XRCC5 |
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