Antibody, Antibody Sampler Kit

Cytoskeletal Marker Antibody Sampler Kit

  • Catalog Number : AK0144
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Introduction

The cytoskeleton consists of three different types of cystosolic fibers: microtubules, microfilaments (actin) and intermediate filaments. Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle β- and γ-actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility. Major types of intermediate filaments are distinguished in part by the tissue in which they are expressed, for example; cytokeratins (epithelial cells), vimentin (mesenchyme origin), and desmin (skeletal, visceral and certain vascular smooth muscle cells). Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form intermediate filaments. Research studies have demonstrated that vimentin is present in sarcomas, but not carcinomas, and its expression is examined relative to other markers in order to distinguish between the two forms of neoplasm. Desmin is a myogenic marker expressed in early development that forms a network of filaments that extends across the myofibril and surrounds Z discs. α/β-tubulin heterodimers form the tubulin subunit that comprises the microtubule building block.

General Information

Reactivity Human, Mouse, Rabbit
Application WB, ELISA
Host Mouse, Rabbit
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Research topic Cytoskeleton

PRODUCT INCLUDES

 

Cat No.

Product name

Quantity

Applications

Reactivity

Host

A340500

Desmin Polyclonal Antibody

20μL

WB, IHC, IF, ELISA

Human, Mouse, Rat

Rabbit

A330116

CK-17 Monoclonal Antibody

20μL

WB, IP

Human

Mouse

A340173

beta Tubulin Polyclonal Antibody

20μL

WB

Human, Mouse, Rat

Rabbit

A340700

Vimentin Polyclonal Antibody

20μL

WB, IHC, IF, ELISA

Human

Rabbit

A340171

beta actin Polyclonal Antibody

20μL

WB, IHC

Human, Mouse, Rat, Monkey, Chicken, Rabbit, Sheep, Xenopus

Rabbit

A1013s

Goat Anti-Rabbit IgG (H+L) (peroxidase/HRP conjugated)

120μL

WB, ELISA

Rabbit

Goat

A1012s

Goat Anti-Mouse IgG (H+L) (peroxidase/HRP conjugated)

120μL

WB, ELISA

Mouse

Goat

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