Antibody, COVID-19 , COVID-19 antibody, COVID-19 Neutralizing Antibody

Anti-SARS-CoV-2 S-IgA Neutralizing Antibody

  • Catalog Number : A510003
  • Number : A510003
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The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

General Information

Application Neutralization
Host Human
Conjugate Non-conjugated
Isotype Human IgA1
Purity ≥95 %
Formula Liquid, may turn slightly opaque during storage
Storage buffer PBS, pH 7.4
Storage instruction 24 months from manufacturing at <-20 °C; 1 month, 2 to 8 °C under sterile conditions.
Alias coronavirus s1,coronavirus s2,coronavirus spike,cov spike,ncov RBD,ncov s1,ncov s2,ncov spike,novel coronavirus RBD,novel coronavirus s1,novel coronavirus s2,novel coronavirus spike,RBD,S1,s2,Spike RBD

Immunoreactivity: 80–120 % compared to the reference sample in an ELISA test.


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