Prolactin (PT0220) mouse mAb
- Catalog Number : A130244
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Introduction
Specificity：This antibody detects endogenous levels of human Prolactin. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section.
Background：prolactin(PRL) Homo sapiens This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Function：
Function: Prolactin acts primarily on the mammary gland by promoting lactation.
Similarity: Belongs to the somatotropin/prolactin family.
Subcellular Location：Cytoplasmic
Background：prolactin(PRL) Homo sapiens This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Function：
Function: Prolactin acts primarily on the mammary gland by promoting lactation.
Similarity: Belongs to the somatotropin/prolactin family.
Subcellular Location：Cytoplasmic
General Information
| Reactivity | Human |
|---|---|
| Application | IHC |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Non-conjugated |
| Uniprot | P01236 |
| Isotype | IgG3, Kappa |
| Immunogen | Synthesized peptide derived from human Prolactin |
| Assay principle | IHC-p 1:100-500 |
| Sample type | paraffin section |
| Purity | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Expression region | Mammary gland,Pituitary,Testis |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instruction | -20°C/1 year |
| Research topic | protein import into nucleus, translocation, protein targeting, protein import into nucleus, intracellular protein transport,nucleocytoplasmic transport, cell surface receptor linked signal transduction, intracellular signaling cascade, protein kinase cascade, JAK-STAT cascade, STAT protein nuclear translocation, female pregnancy, lactation, protein localization, cell proliferation, positive regulation of cell proliferation, positive regulation of signal transduction,regulation of protein kinase cascade, pos |
| Alias | PRL |
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