Antibody, Primary Antibody

NFκB p65 Polyclonal Antibody

  • Catalog Number : A140114
  • Number : A140114-50ug
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Introduction

RELA proto-oncogene, NF-kB subunit(RELA) Homo sapiens NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

General Information

Reactivity Human, Mouse, Monkey
Application WB, IF, ELISA, ICC, IHC-p
Host Rabbit
Clonality Polyclonal
Uniprot Human Q04206;Mouse Q04207
Immunogen The antiserum was produced against synthesized peptide derived from human NF-kappaB p65. AA range:275-324
Assay principle Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300.Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000.
Purity The antibody was affinity-purified from rabbit antiserum by affinitychromatography using epitope-specific immunogen.
Formula Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instruction -20°C/1 year
Alias RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

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