CALCA Rabbit pAb
- Catalog Number : A122444
- Number : A122444
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General Information
| Reactivity | Human, Mouse, Rat | ||||||||||||
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| Application | WB, ELISA | ||||||||||||
| Host | Rabbit | ||||||||||||
| Clonality | Polyclonal | ||||||||||||
| Conjugate | Non-conjugated | ||||||||||||
| Isotype | IgG | ||||||||||||
| Immunogen | Synthesized peptide derived from human protein . at AA range: 71-120 | ||||||||||||
| Molecular Weight | 14kD (Observed) | ||||||||||||
| Storage buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. | ||||||||||||
| Storage instruction | -15°C to -25°C/1 year(Do not lower than -25°C) | ||||||||||||
| Recommeded Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 | ||||||||||||
| Specificity | CALCA Polyclonal Antibody detects endogenous levels of protein. | ||||||||||||
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||||||||
| Gene Name | CALCA CALC1 | ||||||||||||
| Protein Name | Calcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I) | ||||||||||||
| Database Link |
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| Background | CALCA encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for CALCA. | ||||||||||||
| Cellular Localization | Secreted. | ||||||||||||
| Signaling Pathway | Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction | ||||||||||||
| Validation Data |
Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night |
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